Fisher recognized that the evolution of social insect colonies needed explaining, a point which Charles Darwin had avoided discussing in detail. Fisher, in his 1930 book The Genetical Theory of Natural Selection, outlined in detail how eusociality could evolve, and developed a verbal model by connecting selection on fecundity with the sterility of workers. Fisher saw social insect colonies as harmonious units, in contrast to human societies that exhibit intra-communal conflict. Fisher’s development of the model was strongly influenced by his (...) correspondence with Leonard Darwin, and so I call it the Fisher-Darwin model. However, Fisher was not influenced by Lamarckian views on the evolution of social insects that were common at that time. The Fisher-Darwin model presages almost exactly the mathematical model recently proposed by Nowak and colleagues. (shrink)

In his 1961 paper "Tithenai ta Phainomena",1 G. E. L. Owen addressed the problem of the relationship between science as preached in the Analytics and the practice of the Aristotelian treatises. However, he gave this venerable crux a novel twist by focusing on a different aspect of the issue. According to the Prior Analytics , it appears that the first premises of scientific demonstrations must be obtained from collections (historiai) of facts derived from empirical observation. However, many of the (...) treatises seem to make little use of empirical inquiry and instead concern themselves more with 'conceptual analysis.' This is especially true in the Metaphysics and the ethical treatises, but it is also very much characteristic of the Physics. How are these two kinds of inquiry related? (shrink)

This study addressed the lack of implicit measures of religiosity in German research by developing a German Single Category Implicit Association Test for measuring the associative religious self-concept. The SC-IAT was applied to a sample consisting of 389 German students with different subjects of study and internally consistent. To estimate the psychometric criteria of construct validity, SC-IAT scores were correlated to the Centrality of Religiosity Scale, whose construct psychological approach can be theoretically linked to the concept of associative representations in (...) the research on IATs. Corresponding to the average relationship between implicit and explicit measures in literature, the correlation was moderately. Group comparisons relating to religious affiliation and subject of study provided initial evidence for criterion validity. There were complications with the attribute category “non-religious,” especially by participants without a religious affiliation, however, the SC-IAT could also provide a method to investigate this issue. (shrink)

The book also provides insight into overlooked discourses about public sex education by analyzing a previously understudied campaign targeted at African American men in the 1920s, offering theoretical categorizations of discursive ...

This paper analyses Quentin Meillassoux’s criticism of Kantian philosophy. The objective of the paper is to delineate the connection Meillassoux asserts between the problem of induction and Kant’s account of finitude. After examining Meillassoux’s elucidations on the connection between the two, I argue that Meillassoux’s characterization of Kantian philosophy as ‘weak correlationism’ is not only inaccurate but also undermines the novelty of Kantian philosophy, especially Kant’s (critical) response to the problem of induction. The paper concludes with the claim that Meillassoux’s (...) criticism of modern philosophy, especially Kantian critical philosophy, does not convince us to abandon the problem of finitude but points to the need for a more accurate understanding of finitude. (shrink)

Authors and printers together created the New Book of Nature—the printed literature of science—in early modern Europe. Careful attention has been given in recent years to the development of literary and rhetorical techniques in science. This article proposes that these developments were linked to printing technology and the typographic culture that produced the early printed book of science. We focus on several cases in which the roles of author and printer-publisher were joined and thereby highlight connections between knowledge production and (...) reproduction during the Scientific Revolution. Examples include Regiomontanus, Tycho Brake, Galileo, William Leybourn, Joseph Moxon, and the collective practices and privileges of the Royal Society of London and the Paris Academy of Sciences. (shrink)

Major depressive disorder is a highly prevalent psychiatric disorder, and recurrent depression is associated with severe and chronic impairment. Identifying markers of risk is imperative to i...

The powerful combination of genetic, developmental and molecular approaches possible with the fruit fly, Drosophila melanogaster, has led to a profound understanding of the genetic control of early developmental events. However, Drosophila is a highly specialized long germ insect, and the mechanisms controlling its early development may not be typical of insects or Arthropods in general. The beetle, Tribolium castaneum, offers a similar opportunity to integrate high resolution genetic analysis with the developmental/molecular approaches currently used in other organisms. Early results (...) document significant differences between insect orders in the functions of genes responsible for establishing developmental commitments. (shrink)

Prior generations’ electoral crises (e.g., gerrymandering) have dealt mainly with political maneuverings around geographical shifts. We analyze four recent (1998–2003) American electoral crises: the Clinton impeachment controversy, the 2000 Florida presidential election, the Texas legislators’ flight to Oklahoma and New Mexico, and the California gubernatorial recall. We show that in each case temporal manipulation was at least as important as geographical. We highlight emergent electoral practices surrounding the manipulation of time, which we dub “temporal gerrymandering.” We suggest a theory of (...) postmodern electoral crises, in which the rules of time and space are simultaneously in flux. These crises expose concerns with early American democratic theory, which was based on an understanding of “the people” as geographically and temporally unidimensional. Representative systems, therefore, were designed largely without reference to geographic and temporal complexity. (shrink)

Ethical decision-making frameworks assist in identifying the issues at stake in a particular setting and thinking through, in a methodical manner, the ethical issues that require consideration as well as the values that need to be considered and promoted. Decisions made about the use, sharing, and re-use of big data are complex and laden with values. This paper sets out an Ethics Framework for Big Data in Health and Research developed by a working group convened by the Science, Health and (...) Policy-relevant Ethics in Singapore Initiative. It presents the aim and rationale for this framework supported by the underlying ethical concerns that relate to all health and research contexts. It also describes a set of substantive and procedural values that can be weighed up in addressing these concerns, and a step-by-step process for identifying, considering, and resolving the ethical issues arising from big data uses in health and research. This Framework is subsequently applied in the papers published in this Special Issue. These papers each address one of six domains where big data is currently employed: openness in big data and data repositories, precision medicine and big data, real-world data to generate evidence about healthcare interventions, AI-assisted decision-making in healthcare, public-private partnerships in healthcare and research, and cross-sectoral big data. (shrink)

Schulman (Entropy 7(4):221–233, 2005) has argued that Boltzmann’s intuition, that the psychological arrow of time is necessarily aligned with the thermodynamic arrow, is correct. Schulman gives an explicit physical mechanism for this connection, based on the brain being representable as a computer, together with certain thermodynamic properties of computational processes. Hawking (Physical Origins of Time Asymmetry, Cambridge University Press, Cambridge, 1994) presents similar, if briefer, arguments. The purpose of this paper is to critically examine the support for the link between (...) thermodynamics and an arrow of time for computers. The principal arguments put forward by Schulman and Hawking will be shown to fail. It will be shown that any computational process that can take place in an entropy increasing universe, can equally take place in an entropy decreasing universe. This conclusion does not automatically imply a psychological arrow can run counter to the thermodynamic arrow. Some alternative possible explanations for the alignment of the two arrows will be briefly discussed. (shrink)

This study represents an improvement in the ethics scales inventory published in a 1988 Journal of Business Ethics article. The article presents the distillation and validation process whereby the original 33 item inventory was reduced to eight items. These eight items comprise the following ethical dimensions: a moral equity dimension, a relativism dimension, and a contractualism dimension. The multidimensional ethics scale demonstrates significant predictive ability.

Comparative ethics raises theoretical and methodological problems important for all ethical studies. Five essays in this focus section provide introductions to the ethics of specific indigenous cultures and suggest implications for further comparative studies. In this introduction, we review these findings and discuss their relevance to the concept of ethical naturalism which we have previously offered as a basis for comparative work.

Eugene 'Gene' Vernier worked as a fashion photographer for British Vogue from 1954 to 1967, during one of the most exciting periods in fashion history. Shooting of-the-moment looks from the likes of Christian Dior and Emilio Pucci and top models including Celia Hammond, Jean Shrimpton, and current Vogue creative director Grace Coddington, Vernier worked with some of the biggest names in the industry. Yet he was relatively unconcerned with celebrity. Interested only in bringing out the very best in each frame, (...) Vernier was a true craftsman in the fashion photography trade. Featuring more than one hundred of Vernier's own favorite photographs drawn from Vogue's extensive photo archive, this lavishly illustrated volume reveals remarkable innovation in the use of props, backdrops, and location. Whether he was photographing his subjects by the sea, with a canine companion, or perfectly positioned atop a pale pink convertible, Vernier's careful composition enhanced the essence of his subject. Vernier shot mostly in black-and-white, and his trademark “look” is one of classic femininity. He sought to capture models when they were relaxed, enjoying the clothing, and confident that their photographer would show both only at their best. Providing commentary on the photographs are fashion history expert Becky Conekin and Vogue historian Robin Muir. This is first book to focus on Vernier's work at Vogue and it allows readers a rare glimpse of his inimitable blend of technical excellence and an eye for experimentation. (shrink)

In this introductory essay, the authors develop implications for ethical theory which relate to the three studies of cosmogony and ethics in the Focus articles by Guberman, Campany, and Read. They suggest that the dialogue between theory and description which Green and C. Reynolds urge in their Focus article should be understood as a search for adequate forms of ethical theory that must go on in both ethics and comparative studies, as well as in interdisciplinary conversations between them. In considering (...) the descriptive studies in this focus section, and in the collection "Cosmogony and Ethical Order," the authors conclude that the type of ethical theory which will prove most useful for further studies in comparative ethics will be a form of ethical naturalism. (shrink)

The use of social media as a recruitment tool for research with humans is increasing, and likely to continue to grow. Despite this, to date there has been no specific regulatory guidance and there has been little in the bioethics literature to guide investigators and institutional review boards faced with navigating the ethical issues such use raises. We begin to fill this gap by first defending a nonexceptionalist methodology for assessing social media recruitment; second, examining respect for privacy and investigator (...) transparency as key norms governing social media recruitment; and, finally, analyzing three relatively novel aspects of social media recruitment: the ethical significance of compliance with website “terms of use”; the ethics of recruiting from the online networks of research participants; and the ethical implications of online communication from and between participants. Two checklists aimed at guiding investigators and IRBs through the ethical issues are included as appendices. (shrink)

The following suggestions for the interpretation of Parmenides and Melissus can be grouped for convenience about one problem. This is the problem whether, as Aristotle thought and as most commentators still assume, Parmenides wrote his poem in the broad tradition of Ionian and Italian cosmology. The details of Aristotle's interpretation have been challenged over and again, but those who agree with his general assumptions take comfort from some or all of the following major arguments. First, the cosmogony which formed the (...) last part of Parmenides' poem is expressly claimed by the goddess who expounds it to have some measure of truth or reliability in its own right, and indeed the very greatest measure possible for such an attempt. Second, the earlier arguments of the goddess prepare the ground for such a cosmogony in two ways. For in the first place these arguments themselves start from assumptions derived from earlier cosmologists, and are concerned merely to work out the implications of this traditional material. And, in the second place, they end by establishing the existence of a spherical universe: the framework of the physical world can be secured by logic even if the subsequent introduction of sensible qualities or ‘powers’ into this world marks some decline in logical rigour. (shrink)

As opposed to a ‘one size fits all’ approach, precision medicine uses relevant biological, medical, behavioural and environmental information about a person to further personalize their healthcare. This could mean better prediction of someone’s disease risk and more effective diagnosis and treatment if they have a condition. Big data allows for far more precision and tailoring than was ever before possible by linking together diverse datasets to reveal hitherto-unknown correlations and causal pathways. But it also raises ethical issues relating to (...) the balancing of interests, viability of anonymization, familial and group implications, as well as genetic discrimination. This article analyses these issues in light of the values of public benefit, justice, harm minimization, transparency, engagement and reflexivity and applies the deliberative balancing approach found in theEthical Framework for Big Data in Health and Research to a case study on clinical genomic data sharing. Please refer to that article for an explanation of how this framework is to be used, including a full explanation of the key values involved and the balancing approach used in the case study at the end. Our discussion is meant to be of use to those involved in the practice as well as governance and oversight of precision medicine to address ethical concerns that arise in a coherent and systematic manner. (shrink)

The following suggestions for the interpretation of Parmenides and Melissus can be grouped for convenience about one problem. This is the problem whether, as Aristotle thought and as most commentators still assume, Parmenides wrote his poem in the broad tradition of Ionian and Italian cosmology. The details of Aristotle's interpretation have been challenged over and again, but those who agree with his general assumptions take comfort from some or all of the following major arguments. First, the cosmogony which formed the (...) last part of Parmenides' poem is expressly claimed by the goddess who expounds it to have some measure of truth or reliability in its own right, and indeed the very greatest measure possible for such an attempt. Second, the earlier arguments of the goddess prepare the ground for such a cosmogony in two ways. For in the first place these arguments themselves start from assumptions derived from earlier cosmologists, and are concerned merely to work out the implications of this traditional material. And, in the second place, they end by establishing the existence of a spherical universe: the framework of the physical world can be secured by logic even if the subsequent introduction of sensible qualities or ‘powers’ into this world marks some decline in logical rigour. (shrink)